(PTSD) can be an incredibly debilitating condition, but a new treatment has emerged and is available now at Synaptic Psych. PRISM, a cutting-edge digital therapy developed by GrayMatters Health (GMH), is transforming how we approach the neural mechanisms of PTSD.

PRISM is more than just another therapy; it’s a targeted, non-invasive tool that puts the power of healing directly into the patient’s hands.

PRISM Technology and Clearance: A Novel Approach

On March 17, 2023, GrayMatters Health achieved a significant milestone, receiving 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market PRISM for PTSD.

What is PRISM?

Classification: PRISM is regulated as a Class II Self-neuromodulation device. It offers a non-invasive, self-guided adjunct digital therapy for PTSD>
Advanced Neuromodulation: PRISM goes beyond traditional neurofeedback which does not have evidence or approval for PTSD. PRISM is a sophisticated neuromodulation software device designed to train patients to self-regulate their brain activity. The key difference is that it targets a specific, advanced brain biomarker.
Targeting the Amygdala: The core of the technology relies on an advanced biomarker called EEG-fMRI-Pattern (EFP), which fuses high-resolution EEG and fMRI data. The therapy trains patients to lower this amygdala-derived-EFP biomarker, which is directly associated with the amygdala—the brain’s fear and emotion regulation center. By learning to regulate this specific activity, patients gain control over their stress responses.

Clinical Application and Life-Changing Outcomes

PRISM is designed to integrate seamlessly into a patient’s existing treatment plan, serving as an adjunctive treatment alongside other established pharmacological or non-pharmacological interventions.

The Treatment Journey:

Regimen: The therapy is delivered over 15 sessions, typically spanning 8 weeks, with each session lasting about 30 to 45 minutes.
The Patient Experience: During a session, the patient wears an EEG headset and interacts with a captivating interactive audio/visual interface (a computer simulation). This interface reflects their brain activity in real-time. Crucially, this is a non-trauma-based experience, allowing patients to learn control over their stress responses without the necessity of reliving past trauma.

Efficacy that Inspires Hope: In a multi-center clinical study involving patients with chronic PTSD, PRISM demonstrated significant, life-changing symptom improvement:

Significant Improvement: 67% of patients demonstrated clinically significant symptom improvement (a 6-point reduction in CAPS-5 scores) at the 3-month follow-up.
Remission Achieved: A remarkable 32% of patients experienced remission after completing the 15-session regimen.
Holistic Benefits: Significant improvements in sleep, a common challenge for PTSD sufferers, were also observed.

Safety Profile: The treatment’s safety profile is excellent. The most common adverse events were mild and transient, such as headache and fatigue, which resolved naturally without intervention.

In Summary

PRISM is positioned as a promising, novel technology that heralds a new era for PTSD treatment. By utilizing targeted neuromodulation, not just standard neurofeedback, PRISM empowers patients to control the underlying neural mechanisms of their condition. PRISM offers a potent, non-invasive path toward greater emotional regulation and a significant step toward healing.

Come see any of our licensed Clinicians at our 5 locations to learn more!

Synaptic Psych – Brentwood Clinic is located at 5300 Maryland Way Ste 103, Brentwood TN 37027 – Welcome to Synaptic Psych’s Brentwood clinic, where compassionate, cutting-edge mental health care meets the heart of Williamson County. We serve Brentwood, Nolensville, Antioch, and beyond!

Synaptic Psych – Franklin Clinic is located at 381 Riverside Dr Suite 460, Franklin, TN 37064 – Welcome to Synaptic Psych’s Brentwood clinic, where compassionate, cutting-edge mental health care meets the heart of Williamson County. We serve Brentwood, Nolensville, Antioch, and beyond! Our expert team of Brentwood Psychiatrists offers a full spectrum of behavioral health services

Synaptic Psych – Nashville Clinic is located at 2125 Belcourt Ave, Nashville, TN 37212. – Welcome to Synaptic Psych’s Nashville clinic, where compassionate, cutting-edge mental health care meets the heart of Davidson County. Our expert team of Nashville Psychiatrists and Nashville Child Psychiatrists offers a full spectrum of behavioral health services

Synaptic Psych – East Nashville Clinic is located at 3800 Gallatin Pike, Nashville TN 37216 – Welcome to Synaptic Psych’s East Nashville clinic, where compassionate, cutting-edge mental health care meets the heart of Davidson County. Our expert team of East Nashville and Inglewood Psychiatrists offers a full spectrum of behavioral health services

Synaptic Psych – 871 Ridgeway Loop Road, Suite 108 Memphis TN 38120 – Welcome to Synaptic Psych’s Memphis clinic, where compassionate, cutting-edge mental health care meets the heart of Shelby County. Our expert team of Memphis and Germantown Psychiatrists and behavioral health experts offers a full spectrum of behavioral health services