Nasal Esketamine
Esketamine for Depression
We offer the only FDA-approved ketamine-based treatment for depression. Nasal esketamine (Spravato®), is a safe, physician-supervised, psychedelic nose spray therapy that is covered by many insurances. Often, nasal esketamine is effective at treating depression in patients who have been unable to find relief through other methods, like talk therapy and antidepressants. Learn more about esketamine treatment and determine if it might be right for you.
How does it work?
It is believed, based on the current research, that Ketamine disrupts the brain chemical glutamate. Glutamate is involved vvith learning, memory, emotion, and pain recognition. Ketamine can cause rapid heart rate and elevated blood pressure.
Esketamine is a part of ketamine, and was made to be more potent in its nasal form, so you can use this medication at a lower dose and, likely, have fewer side effects.
Esketamine must be used in conjunction with a conventional antidepressant and is regulated through a federally mandated risk mitigation program. Esketamine can provide rapid relief from depression symptoms and suicidality.
Learn more about Esketamine.
Esketamine is made from a drug called ketamine, which was first used in clinical practice as an anesthetic (sedative). In the 1970s, ketamine's use for the treatment of psychiatric disorders was first noted and has been studied formally since the 1990s. In 2019, the FDA approved nasal esketamine, a ketamine-based nasal spray for adults with treatment-resistant depression (TRD) and adults with major depressive disorder (MDD) - sometimes called Clinical Depression - with suicidal thoughts or behavior. TRD simply means that standard treatment methods have not been able to successfully treat the depressive episode.
Although you may have also heard of ketamine as a psychedelic street drug with names such as 'Special K' or 'K', its use can be safe when under the supervision of a trained clinician. To learn more, check out our Esketamine: VIDEO BLOG POST - Busting the Myths, where we dispel some of the most common misconceptions about this medication.
Is Esketamine (Spravato®) right for me?
Esketamine is not right for everyone. However, for the right people, it shows great promise. We would love for you to speak with a member of our Interventional Services Team to see if Spravato (Esketamine) might be a good fit. Please complete this screening questionnaire and a team member will reach out to you.
If you've tried other depression treatments (medications, therapy, TMS, or even ECT) without success, there is still hope. In fact, most of our patients have tried several types of treatments before finding success with nasal esketamine.
Covered by many
insurance plans
FDA-cleared and
clinician-supervised
Knowledgable and
experienced staff
Treatment in a safe and comfortable environment.
Your comfort and safety are our top priortities. Since esketamine, like ketamine, is a psychedelic treatment, you may experience feelings like euphoria, dizziness, or intoxication. Our expert care team will be available onsite, and will also closely monitor you and your blood pressure throughout treatment. Learn more about esketamine treatment, including what to expect and how to prepare.
Typical Course of Treatment
Each patient is unique and will receive their own individualized care plan. However, the treatment course for nasal esketamine typically starts with two treatments per week for the first four weeks, followed by one treatment per week for four to eight weeks, before being reduced. The goal is to reduce treatment frequency to once per month. Esketamine must be used in conjunction with a conventional antidepressant.
2 treatments per
week for 4 weeks
1 treatment per
week for 4 to 8 weeks
1 treatment every
3 to 5 weeks
2 treatments per
week for 4 weeks
1 treatment per
week for 4 to 8 weeks
1 treatment every
3 to 5 weeks
Esketamine & Ketamine: Busting the Myths
Learn more about ketamine and nasal esketamine in our blog post, Esketamine: Busting the Myths.
Check out our blog.
We strive to educate, empower, and inspire patients to help them lead happier, healthier lives. Check out our blog for news and helpful information, expert tips, answers to some of your most frequently asked questions, and much more.
Which heuristic should a clinician use?
Dr Cochran and Dr. Kerns demonstrated heuristics for placement of TMS Coils including the BEAM and a modified BEAM methods while at the LONDON, UK PULSES course on […]
Successful PULSES course in LONDON, UK
Dr Cochran and Lauren Valencia LCSW, our TMS Supervisor, were honored to speak on behalf of the CTMSS society in London July 5 & 6th. Several junior doctors […]
Lecturing in London, UK
Lauren Valencia, LCSW and Dr. Cochran traveled to the United Kingdom over the July 4th holiday. Lauren’s lecture was was delightful and poised and a highlight of the […]
Electromagnetism
From Dr. Cochran, “A colleague of mine, says frequently, ‘if not for Mr Faraday’ there would be no TMS. While in London, UK in February 2018, I had […]
We wrote the book!
Dr Cochran is announced the full launch of TMS Workbook in April 2019. Train Your Brain Your record of care with transcranial magnetic stimulation Written by Dr. Cochran and her team, this workbook, now […]
Five Reasons to pick our office!
While attending the recent International Conference, Dr. Cochran was asked, “what are you doing to get your remissions rates so high?” After a long pause, she responded, “Good […]
TMS Technician – Kayla Evans
We are excited to have Kayla Evans join our team with our growing TMS service as part of the NeuroScience and TMS Treatment Centers.
Lectures in San Francisco – May 2019
Dr Cochran and Lauren Valencia, LCSW spoke at the PULSES conference in May. This conference is held 3-4 times per year, at least once internationally (July 2019 in […]
Dr. Cochran awarded the CTMSS President’s Award
Dr. Cochran was awarded the president’s award for The Clinical TMS Society at the annual meeting in Vancouver, BC – February 2019. The award was given to Dr. […]
PULSES February 2019
Dr Cochran and Lauren Valencia, LCSW were both faculty at the PULSES – two day conference that proceeded the Clinical TMS Society’s annual meeting in February 2019. Both […]
Physician Recommended.
Patient Preferred.
Dr. Cochran at The Neuroscience and TMS center has served as my psychiatric care physician for the past 5 years. I have made tremendous progress while seeing her. She is attentive, thorough, and professional. I refer her to everyone I know in need of psychiatric care because I trust her and her staff completely. I am very thankful to be a patient of the Neuroscience and TMS center.
-CL
This hands down is the BEST doctor’s office I've ever been to. Not just on a psychiatric level, but just a medical setting in general. I love Dr. Becker and I'm beyond grateful that I found him. He is very personable and just one of the easiest people to talk to. And the front desk is great too and that goes a long way! So yes, 5 stars! I recommend this to anyone who needs to find a good and relaxed environment for psychiatry.
-MM
Mary is wonderful. She understands my medical condition and truly cares. She listens and comforts you in time of need. She is a true human being and doesn’t treat you like a number. She is very professional and knows her stuff.
-AC
Ali was amazing. We have searched for help for years for our son. It was nice for her to listen but then give great advice!! We are in the process of implementing her parenting plan and It is not easy but we can already see a difference!!
-ER
This was a great treatment for me. I have completed TMS therapy numerous times b/c I keep getting better and better. I suffered a traumatic brain injury and was steered towards TMS and it has helped me tremendously…This team knows what they are doing and I’m happy I had the opportunity to do this.
-JP
The staff are 100% committed to the clients’ health and well-being. They find solutions tailored to the individual’s needs and goals. If I could leave 10 stars, I would. ⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️
-HH
Everyone from Dr. Becker on down has done an outstanding job. Professional and caring that is hard to find in medicine today and you guys provide both!! And, Emily is a real gem as the TMS tech.
-EPC, MD [VUMC]
We are here for you.
Want to learn more about one of our treatments or services?
Need to schedule an appointment or have a question about your care plan? We're here for you! To reach any office
Call 615.224.9800
Email support@hopeforyourbrain.com
Secure Text Line (615) 551-5853
Fax (615) 224-9840, or
Complete the Form Below